As the summer approaches we start drinking more. A cold pint in a beer garden on a sun is a pleasure, but what's the science behind world most popular legal drug? Which grandma's advices are actually true, and which are completely, utterly ridiculous? Lets' s look at some myths, stereotypes and research behind the substance, that kills around 100,000 people globally every year (computed by Wolfram Alpha).
1. Alcohol is a poison.
TRUE. And naturally humans produce a defence against it - an enzyme called 'alcohol dehydrogenase' (AD). This enzyme is a way your body fights back booze and gets you sober. The enzyme grabs hydrogene from ethanol molecule and makes it non-toxic acetaldehyde. Well, it's non-toxic, but a high cumulation of it will eventually cause dehydration and hangover.
2. Asians bodies don't produce alcohol dehydrogenase.
FALSE. It's a genetic variation that caused some of them produce less than in Caucasians. Variation was large enough to affect 1/3 of Asian drinker's population. Their great-great-grandparents simply didn't get so wasted Friday night as in Caucasian culture.
3. Women get easier drunk than man.
PARTIALLY TRUE. There are many factors, but generally AD enzyme mentioned previously is much more effective in man than women (70-80% greater activity in man than woman). However there is a tradeoff - AD enzyme activity drops much quicker for man than for women with age - so later in life those differences disappear.
4. Better eat before you get pished.
TRUE, but not because food 'soaks' the alcohol. When your stomach is full, it closes a small valve that leads to your small intestine (called 'pyloric sphincter'), so your stomach will have time to process the food before it gets to high-absorption intestine. If you drink on empty stomach - your pyloric sphincter is wide open and leading straight to 200 square meters of absorption surface in the small intestine that will happily suck the alcohol into your blood stream very fast and get you knocked.
5. If I drink one-half-pint-per-hour, I should be ok to drive us home.
WRONG. Your alcohol absorbtion and elimination is a curve, not a straight function.
6. Drunk bums live longer.
TRUE, to some extend ;-) Surprised? Well, in the recent study published in Alcohol: Clinical and Experimental Research journal, Holahan et al. (2010) followed 1824 people over a total of 20 years, as they aged between 55 and 65. Of those who totally abstained 69% died. From 'light drinkers' - 64% died. Among those who drunk 'moderately' - 41% died. Even heavy drinkers did better than abstinents and light drinkers - 61% of them passed away during the study.
As the summer hits, this topic will get covered more, with other drugs too, so stay tuned.
As the summer hits, this topic will get covered more, with other drugs too, so stay tuned.